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“Can’t Get High” Syndrome: A Terrible Affliction

Can't Get High? You're like Amanda


“Can’t Get High” Syndrome: A Terrible Affliction

Did you know some people can’t get high? Does it affect you or a loved one? With so many options for enjoying cannabis out there today—from vaporizers to edibles to tinctures, oils, buds and blunts (and the list goes on)—it seems impossible that the aspiring toker would be unable to find a way to get high that works.

But the truth is this: some folks just can’t get high, no matter how much they try. Sadness.

Maybe it takes a few tries, but most people who experiment with pot know what it feels like to be high. The laments of one Buffalo-area woman, however, paint a different story.

She just can’t get high! Green Rush Daily caught up with Amanda G. to ask about this unusual phenomenon. “I’ve tried it all, and believe me, experts have coached me.” For several years, Amanda has embraced every opportunity to get on board the marijuana train.

“Cleared a 3-foot bong. Nothing but coughs. Ate enough baked goods to sedate a rhino. Maybe a sugar high. But that was it!” Amanda even said she was working on her deep-inhalation skills, “Lately I’ve been practicing yoga breathing exercises to prepare myself better for taking huge rips and holding them in for up to a minute. I was, and still am, willing to try anything.”

Can’t get high? It may be your hormones

In a paper published last year in the journal Science, researchers at the French National Institute of Health and Medical Research found that pregnenolone, a hormone the body produces naturally, can counter the effects of THC, the component in marijuana that creates the drug’s famous high. So the bodies of some people make them natural buzz-kills.

Still, the discovery of the hormone pregnenolone and its effects on THC is a breakthrough in the medical cannabis community and may be a solution for patients who wish to take medicinal herb but who are averse to getting high.

“These researchers weren’t trying to be buzzkills,” read Science. “Their discovery could lead to new approaches to treating marijuana intoxication and addiction, and it may allow researchers to isolate the medicinal properties of cannabis while blocking its behavioral and somatic effects.”

The existence of a hormone that blocks the effects of THC is no consolation to Amanda and people like her who can’t get high, but want to. They’ll either have to keep trying or resign themselves to this cruel fate.

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